(EMAILWIRE.COM, May 29, 2019 ) The rising demand for synthesized oligos in molecular diagnostics & therapeutics, increasing R&D expenditure by pharmaceutical and biotechnology companies, rising venture capital investments, and the increasing demand for synthetic genes are the major factors driving the growth of this market.

Therapeutic applications segment to grow at the highest CAGR during the forecast period

Based on application, the oligonucleotide synthesis market is segmented into research, diagnostic, and therapeutic applications. The therapeutic applications segment, which is further segmented into RNAi oligonucleotide-based therapies, DNA & antisense oligonucleotide-based therapies, and CpG oligonucleotide-based therapies, is estimated to witness the highest growth during the forecast period. This can primarily be attributed to the investments made by companies to explore the therapeutic applications of oligos.

Also, from 2016 to 2018, more than five oligonucleotide-based therapies were approved by the FDA. In 2018, these oligonucleotide-based drugs generated a revenue of ~USD 2 billion. Apart from this, there are a couple of oligonucleotide-based drugs in Phase III and FDA review, and these drugs might be launched in the next five years and may positively impact this market.

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Hospitals accounted for the largest share of the oligonucleotide synthesis market, by end user, in 2018

Based on end user, the oligonucleotide synthesis market is segmented into academic research institutes, diagnostic laboratories, pharmaceutical & biotechnology companies, and hospitals. Hospitals accounted for the largest share of the oligonucleotide synthesis market in 2018. Growth in this end-user segment is largely driven by the significant number of inpatient and outpatient visits in hospitals and the high requirement of oligonucleotide drugs to cater to the demand from the vast patient pool suffering from diseases such as Duchenne muscular dystrophy, spinal muscular atrophy, and hepatic veno-occlusive disease.

North America was the largest regional market for oligonucleotide synthesis in 2018

The oligonucleotide synthesis market is segmented into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. In 2018, North America accounted for the largest share of the oligonucleotide synthesis market majorly due to the availability of funds for research from various public- and private-sector organizations in the region and the focus of various prominent players on strengthening their presence in North America through product launches and strategic acquisitions and collaborations & agreements. Europe was the second-largest regional market for oligonucleotide synthesis in 2018. This can be attributed to factors such as the presence of a large number of academic and research institutes in the region, growing investments by government bodies and market players, and the increasing focus on R&D activities.

The prominent players operating in the oligonucleotide synthesis market include BioAutomation Corporation (US), LGC Biosearch Technologies (US), Eurogentec (Belgium), GeneDesign, Inc. (Japan), Sarepta Therapeutics (US), Thermo Fisher Scientific, Inc. (US), Agilent Technologies, Inc. (US), GenScript, Inc. (US), Integrated DNA Technologies (IDT, US), Nitto Denko Avecia, Inc. (US), TriLink BioTechnologies (US), Biogen International (US), ATDBio Ltd. (UK), Bio-Synthesis, Inc. (US), Eurofins Genomics (Germany), GE Healthcare (US), Sigma-Aldrich Corporation (a part of Merck KGAA, US), and Sarepta Therapeutics (US).

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