(EMAILWIRE.COM, January 07, 2021 ) According MarketsandMarkets Research - The report "COVID-19 Impact on Vaccines and Drugs Market - Global Forecast to 2025"The COVID-19 impact on the global vaccines market size is estimated at USD 2,273 million in 2022 and projected to reach USD 1,401 million by 2025, resulting in a CAGR of -14.9%. On the other hand, the COVID-19 impact on the global drugs market size is anticipated at 165 million in 2020 and estimated to reach USD 2 million by 2025, at a CAGR of -57.8%.

With the first vaccine for COVID-19 expected to enter the market in the next 12 – 18 months, North American manufacturers have the largest number of potential vaccine candidates in the pipeline.

As of April 8, 2020, the R&D landscape for COVID-19 vaccines includes 115 vaccine candidates, of which 78 are confirmed as active, and 37 are unconfirmed (development status cannot be determined from publicly available or proprietary information sources). Of the 78 confirmed active projects, 73 are currently in the exploratory or preclinical stages. The most advanced candidates that have recently moved into clinical development are:

- mRNA-1273 from Moderna
- Ad5-nCoV from CanSino Biologics
- INO-4800 from Inovio
- LV-SMENP-DC and pathogen-specific aAPC from Shenzhen Geno-Immune Medical Institute.

Other prominent players in the vaccines market have also entered the race of launching inoculations targeting COVID-19, such as GSK and Sanofi. Sanofi and GSK are coming together to work on a COVID-19 vaccine, which, if it passes clinical trials, will become available in the next 12- 18 months timeline.

Developers of active COVID-19 vaccine candidates are distributed across 19 countries, which collectively account for over three-quarters of the global population. Of these, North American manufacturers are leading with the most number of potential vaccines in the pipeline.

Request Research Sample Pages: https://www.marketsandmarkets.com/requestsampleNew.asp?id=112248051

Vaccine manufacturing ramp-up to drive the growth further
While global drug makers are pouring massive resources into developing targeted therapies and vaccines, contract development and manufacturing organizations (CDMOs) are finding ways to ramp up the production of vaccines. In line with this, a new CDMO from Belgium's Univercells is offering its expertise to help drug makers scale up their manufacturing.

Pfizer and BioNTech have initiated plans for clinical trials and producing millions of doses, if the trials succeed. The companies expect to have millions of doses of a COVID-19 vaccine ready to go by year-end if the companies begin human testing as planned by late April. Pfizer and BioNTech are hoping to advance multiple mRNA vaccine candidates.

Currently, around 155 molecules are under clinical investigation, and about 45 molecules are under preclinical development to be targeted against COVID-19. In this list, four promising drugs have been repurposed for use against COVID-19.

- Remdesivir
- Chloroquine and hydroxychloroquine
- Lopinavir and ritonavir (and that same combination plus interferon-beta)
- An immune system messenger that can help stop the multiplication of viruses.

Download PDF Brochure: https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=112248051

Key Market Players;

Key players in the COVID-19 vaccines market include Pfizer Inc. (US), Johnson & Johnson Services, Inc (US), GlaxoSmithKline plc. (UK), Sanofi (France) Serum Institute of India (India), among others. Major players in the COVID-19 drugs market include Gilead Sciences, Inc. (US), Sanofi (France), F. Hoffmann-La Roche Ltd (Switzerland), Merck KGaA (Germany), Janssen Pharmaceuticals, Inc. (Belgium) among others.